Electrolytes
Nausea, vomiting, and reduced fluid intake are common on GLP-1 medications and can quickly lead to dehydration. Your kidneys also excrete more sodium when eating fewer carbohydrates, compounding electrolyte losses. Oral rehydration-style electrolyte products โ rather than sugary sports drinks โ are what clinical guidance recommends for this population.
How we chose these products
Every product in this category is assigned an evidence tier โ Strong, Moderate, or Emergingโ based on the clinical research behind the key ingredient category. Products labeled โGLP-1 Specifically Labeledโ are formulated or marketed directly for GLP-1 medication users.
Our composite score weights evidence tier, Amazon rating, and review volume. Products are sorted by composite score by default. We earn affiliate commissions on purchases, which does not influence our ratings.
What to look for
Look for a sodium-forward formula: 500โ1000mg of sodium per serving is the target for GLP-1-related dehydration. Most commercial sports drinks contain far too little sodium and too much sugar to be effective.
Oral rehydration salts (ORS) โ the standard recommended by WHO for dehydration treatment โ use a specific sodium-to-glucose ratio to maximize absorption. Products formulated to this standard are more effective than flavored water with trace minerals.
Avoid stimulant-added electrolyte products if you're already sensitive to caffeine from reduced food intake. Plain electrolyte products without caffeine or herbal additives are safer and better tolerated.
Top picks โ 15 products
Ships from brand website
Drink LMNT
LMNT Zero Sugar Electrolytes
Also available in: 12-count, 18-count bundle, Raw Salt 30-count, and 30+ other flavors
Herbtonics
Herbtonics Apple Cider Vinegar + Keto BHB Capsules | GLP-1 Support for Appetite
GLP-1 Labeled
Stur
Stur Electrolyte Water Enhancer | Sweetened with Stevia | High in Antioxidant Vitamin C | Sugar Free | Zero Calories | Keto | Vegan | 5 Bottles
Stevia-sweetened version. Stur also makes an unsweetened electrolyte drop for those avoiding all sweeteners.
Stur
Stur Electrolyte Drops | Source of B Vitamins for Instant Hydration | No Sugar
Unsweetened version. Stur also makes a stevia-sweetened electrolyte enhancer for those who prefer a light flavor.
Dr. Berg Nutritionals
Dr. Berg Zero Sugar Hydration Keto Electrolyte Powder - Enhanced w/ 1000 mg of Potassium & Real Pink Himalayan Salt
DripDrop
DripDrop Hydration Packets - Juicy - Single Serve Electrolytes Powder Drink Mix - Lemonade - Non-GMO
Related reading
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Frequently asked questions
Why do GLP-1 medications cause dehydration?
GLP-1 medications cause dehydration through multiple pathways: nausea and vomiting directly lose fluids and electrolytes, reduced food intake means less water absorbed from food, eating fewer carbohydrates causes kidneys to excrete more sodium, and reduced appetite often leads to reduced thirst and fluid intake.
What electrolytes are most depleted on Ozempic or Mounjaro?
Sodium is typically the most depleted electrolyte on GLP-1 therapy, followed by potassium and magnesium. Sodium is lost through reduced carbohydrate intake and through vomiting. Magnesium deficiency is also common with reduced food intake and is linked to fatigue and muscle cramps.
How much should I drink on GLP-1 medications?
Aim for at least 8โ10 cups (2โ2.5 liters) of fluid daily on GLP-1 therapy. If experiencing nausea or vomiting, prioritize electrolyte-containing fluids over plain water. Small, frequent sips are better tolerated than large amounts at once.
Can I use sports drinks like Gatorade on Ozempic?
Standard sports drinks like Gatorade are not ideal for GLP-1-related dehydration โ they contain too much sugar and too little sodium. Oral rehydration solutions (ORS) or low-sugar electrolyte products with 500โ1000mg sodium per serving are significantly more effective.